The 6 handshakes rule, also known as the 6 degrees of separation theory, claims that we can get to know anyone by connecting through 6 people, or even fewer. A “degree of separation” is a measure of social distance between human beings. Through this piece, I will give the historical background behind this theory and will share my own personal connection to it. Appealingly, a part of this article is dedicated to the studies that have elaborated on this matter, and its relation to the current pandemic.